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But the sole four-MAR/Aminorex typre drug we have witnessed is four,4-Dimethylaminorex, and which was chargeable for a variety of deaths. We know from phendimetrazine that substitutions to the Nitrogen lessen the potency or need to be demthylated in vitro rendering it a prodrug.3-Fluorophenmetrazine has not been formally reviewed by WHO and isn't c